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NIAID Renews Funding for National Emerging Infectious Diseases Research Network

2009-06-09 The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, today announced renewed funding for 10 previously established Regional Centers of Excellence for Biodefense and Emerging Infectious Diseases Research (RCE). NIAID also awarded funds to Oregon Health & Science University to establish a new RCE to be based in the Pacific Northwest. NIAID funding for the 11 RCEs totals up to approximately $455 million over five years.

2007-07-05 Recent research done in collaboration with MRCE investigators at Washington University and St. Louis University have identified single nucleotide polymorphisms (SNPs) that underlie susceptibility to fever after smallpox vaccination. The study's results raise the possibility that the SNPs linked to fever following smallpox vaccination may also influence fever risk following vaccination with other live-virus vaccines. Fever is a common side-effect from the childhood measles, mumps and rubella vaccine. This discovery resulted in a collaborative research effort between Dr. Samuel L. Stanley Jr.’s laboratory at Washington University and Drs. Robert Belshe and Sharon Frey at St. Louis University. The study results are published in the July 15, 2007 issue of the Journal of Infectious Diseases.

An interview about the article can be downloaded here.

2007-02-07 The MRCE awarded a fellowship to area investigator Dr. Brian Edelson through its Clinical/Translational Fellowship Program. The fellowship will support Dr. Edelson's ongoing work on understanding the development and heterogeneity of innate immune cells. His work will be carried out under the mentorship of Washington University School of Medicine investigator Dr. Kenneth M. Murphy.

2007-02-02 Recent research from the laboratory of MRCE Developmental Project Investigator Dr. William Goldman and MRCE Clinical Translational fellow Dr. Wyndham Lathem has shown that the plasminogen activator Pla is essential for Yersinia pestis to cause primary pneumonic plague but is less important for dissemination during pneumonic plague than during bubonic plague. Their results suggest that inhibition of Pla during primary pneumonic plague may prolong the survival of the affected individual, expanding the window during which antibiotics could be successfully administered to treat the disease. The results are published in the January issue of Science.

A recent press release of the article can be found here.

2007-01-16 Recent research from the laboratory of MRCE Strategic Project Investigator Dr. Herbert Virgin has identified a role for the interferon stimulated gene 15 (ISG15) in combating infection by flu, herpes and the SindBis virus. The results are published this week in the online edition of Proceedings of the National Academy of Sciences.

A recent press release of the article can be found here.

MRCE Hires New Senior Project Manager

2006-10-16 We are pleased to announce that Dr. Scott A. Handley has join the MRCE as our new Senior Project Manager. Dr. Handley is an outstanding young scientist who just completed his doctoral work. Please join us in welcoming Scott into the MRCE group. You may direct your questions or comments to Dr. Handley at (314) 286-0192 or shandley@mrce.wustl.edu.

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