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Tumor necrosis factor alpha protects against lethal West Nile virus infection by promoting trafficking of mononuclear leukocytes into the central nervous system. Shrestha B, Zhang B, Purtha WE, Klein RS, Diamond MS. J Virol: 2008 Sep;82(18):8956-64 .

CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis. McCandless EE, Zhang B, Diamond MS, Klein RS. Proc Natl Acad Sci U S A: 2008 Aug 12;105(32):11270-5 .

Interferon regulatory factor (IRF)-7 induces the antiviral interferon (IFN)-{alpha} response and protects against lethal West Nile virus infection. Daffis S, Samuel MA, Suthar MS, Keller BC, Gale M Jr, Diamond MS. J Virol: 2008 Jun 18 [ .

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The relative contribution of antibody and CD8+ T cells to vaccine immunity against West Nile encephalitis virus. Bimmi Shresthaa, Terry Ngb, Hsien-Jue Chub, Michelle Nolla and Michael S Diamond. Vaccine: 2008 Apr 7;26(16):2020-33 .

CXCR3 Mediates Region-Specific Antiviral T Cell Trafficking within the Central Nervous System during West Nile Virus Encephalitis. Zhang B, Chan YK, Lu B, Diamond MS, Klein RS. J Immunol: 2008; 180(4):2641-9 .

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins. Lok SM, Kostyuchenko V, Nybakken GE, Holdaway HA, Battisti AJ, Sukupolvi-Petty S, Sedlak D, Fremont DH, Chipman PR, Roehrig JT, Diamond MS, Kuhn RJ, Rossmann MG. Nat Struct Mol Biol: 2008 Mar;15(3):312-7 .

Defining the Levels of Secreted Non-Structural Protein NS1 After West Nile Virus Infection in Cell Culture and Mice. Kyung Min Chung and Michael S Diamond. Journal of Medical Virology: 2008;80:547-556 .

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Fas Ligand interactions contribute to CD8+ T cell-mediated control of West Nile virus infection in the central nervous system. Shrestha B, Diamond MS. Journal of Virology: 2007;81(21):11749-11757 .

Induction of Epitope-Specific Neutralizing Antibodies against West Nile virus. Oliphant T, Nybakken GE, Austin SK, Xu Q, Bramson J, Loeb M, Throsby M, Fremont DH, Pierson TC, Diamond MS. J Virol: 2007;81(21):11828-11839 .

CD40-CD40 Ligand Interactions Promote Trafficking of CD8+ T Cells into the Brain and Protection against West Nile Virus Encephalitis. Sitati E, McCandless EE, Klein RS, Diamond MS. J Virol: 2007;81(18):9801-9811 .

Antibody recognition of cell surface-associated NS1 triggers Fc-y receptor mediated phagocytosis and clearance of WNV infected cells. Kyung Min Chung, Bruce S Thompson, Daved H Fremont, and Michael S Diamond. J Virol: 2007;81(17):9551-9555 .

Antigen-specific cytotoxic T lymphocytes protect against lethal West Nile virus encephalitis. Purtha WE, Myers N, Mitaksov V, Sitati E, Connolly J, Fremont DH, Hansen TH, Diamond MS. Eur J Immunol : 2007;37:1845-1854 .

The molecular basis of antibody-mediated neutralization of West Nile virus. Theodore Oliphant, Michael S Diamond. Expert Opin Biol Ther: 2007;7(6):885-892 .

Defining limits of humanized neutralizing monoclonal antibody treatment for West Nile virus neurological infection in a hamster model. Morrey JD, Siddharthan V, Olsen AL, Wang H, Julaner JG, Hall JO, Li H, Nordstrom JL, Koenig S, Johnson S, Diamond MS. Antimicrob Agents Chemother: 2007;51(7):2396-2402 .

West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H. Chung KM, Liszewski MK, Nybakken G, Davis AE, Townsend RR, Fremont DH, Atkinson JP, Diamond MS. Proc Natl Acad Sci U S A: 2006;103(50):19111-19116 .

CD4+ T Cell Responses are Required for Clearance for West Nile Virus from the Central Nervous System. Sitati EM, Diamond MS. J Virol: 2006;80(24):12060-12069 .

Pathogenesis of West Nile Virus Infection: a Balance between Virulence, Innate and Adaptive Immunity, and Viral Evasion. Samuel MA, Diamond MS. J Virol: 2006;80(19):9349-9360 Review .

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Antibodies against West Nile Virus nonstructural protein NS1 prevent lethal infection through Fc gamma receptor-dependent and -independent mechanisms. Chung KM, Nybakken GE, Thompson BS, Engle MJ, Marri A, Fremont DH, Diamond MS. J Virol: 2006;80(3):1340-1351 .

Structure, expression and intracellular localization of the SARS-CoV accessory proteins 7a and 7b. Pekosz A, Schaecher SR, Diamond MS, Fremont DH, Sims AC, Baric RS. Adv Exp Med Biol: 2006;581:115-120 .

Structural basis of West Nile Virus neutralization by a therapeutic antibody. Nybakken GE, Oliphant T, Johnson S, Burke S, Diamond MS, Fremont DH. Nature: 2005;437:764-769 .

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Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus. Oliphant T, Engle M, Nybakken GE, Doane C, Johnson S, Huang L, Gorlatov S, Mehlhop E, Marri A, Chung KM, Ebel GD, Kramer LD, Fremont DH, Diamond MS. Nat Med: 2005;11(5):522-530 .

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Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity. Hildner K, Edelson BT, Purtha WE, Diamond M, Matsushita H, Kohyama M, Calderon B, Schraml BU, Unanue ER, Diamond MS, Schreiber RD, Murphy TL, Murphy KM. Science: 2008 Nov 14;322(5904):1097-100 .

A therapeutic antibody against west nile virus neutralizes infection by blocking fusion within endosomes. Thompson BS, Moesker B, Smit JM, Wilschut J, Diamond MS, Fremont DH. PLoS Pathog: 2009 May;5(5):e1000453 .

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Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins. Lok SM, Kostyuchenko V, Nybakken GE, Holdaway HA, Battisti AJ, Sukupolvi-Petty S, Sedlak D, Fremont DH, Chipman PR, Roehrig JT, Diamond MS, Kuhn RJ, Rossmann MG. Nat Struct Mol Biol: 2008 Mar;15(3):312-7 .

Human MHC class I molecules with disulfide traps secure disease-related antigenic peptides and exclude competitor peptides. Steven M Truscott, Xiaoli Wang, Lonnie Lybarger, William E Biddison, Cortez McBerry, John M Martinko, Janet M Connolly, Gerald P Linette, Daved H Fremont, Ted H Hansen and Beatriz M Carreno. Journal of Biological Chemistry: 2008 Mar 21;283(12):7480-90 .

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Structural Engineering of pMHC Reagents for T Cell Vaccines and Diagnostics. Mitaksov V, Truscott SM, Lybarger L, Connolly JM, Hansen TH, Fremont DH. Chem Biol: 2007;14(8):909-922 .

Antibody recognition of cell surface-associated NS1 triggers Fc-y receptor mediated phagocytosis and clearance of WNV infected cells. Kyung Min Chung, Bruce S Thompson, Daved H Fremont, and Michael S Diamond. J Virol: 2007;81(17):9551-9555 .

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Disulfide bond engineering to trap peptides in the MHC class I binding groove. Truscott SM, Lybarger L, Martinko JM, Mitaksov VE, Kranz DM, Connolly JM, Fremont DH, Hansen TH. J Immunol: 2007;178(10):6280-6289 .

West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H. Chung KM, Liszewski MK, Nybakken G, Davis AE, Townsend RR, Fremont DH, Atkinson JP, Diamond MS. Proc Natl Acad Sci U S A: 2006;103(50):19111-19116 .

Structural Determinants of Chemokine Binding by an Ectromelia Virus-Encoded Decoy Receptor. Arnold PL, Fremont DH. J Virol: 2006;80(15):7439-7449 .

Crystal structure of the West Nile virus envelope glycoprotein. Nybakken GE, Nelson CA, Chen BR, Diamond MS, Fremont DH. J Virol: 2006;80(23):11467-11474 .

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Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus. Oliphant T, Engle M, Nybakken GE, Doane C, Johnson S, Huang L, Gorlatov S, Mehlhop E, Marri A, Chung KM, Ebel GD, Kramer LD, Fremont DH, Diamond MS. Nat Med: 2005;11(5):522-530 .

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Structural Engineering of pMHC Reagents for T Cell Vaccines and Diagnostics. Mitaksov V, Truscott SM, Lybarger L, Connolly JM, Hansen TH, Fremont DH. Chem Biol: 2007;14(8):909-922 .

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